NeurosciencebioRxivPreprint
Single-cell atlas of the fetal Down syndrome cortex uncovers chromosome 21 regulators of intellectual disability gene networks
Michael Lattke, Wee Leng Tan, Salil Kalarikkal Sukumaran…·Vincenzo De Paola
The paper constructs a single-cell atlas of fetal Down syndrome cortex, identifying chromosome 21 transcription factors that regulate intellectual disability gene networks and showing their normalization can restore molecular signatures.