Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila
Jayati Gera, Marishia Agard, Hannah Nave, Austin B Baldridge, Farwa Sajadi, Leena Thorat, Theresa H McKim, Shu Kondo, Dick R Nässel, Mitchell H Omar, Jean-Paul Paluzzi, Meet Zandawala
This paper characterizes the ITP signaling system in Drosophila, identifying ITPa as an anti-diuretic hormone that acts via the Gyc76C receptor to modulate osmoregulation and metabolic homeostasis.
bioRxiv · Feb 7, 2024Physiology