In Vitro and Viral Evolution Convergence Reveal the Selective Pressures Driving Omicron Emergence
Aviv Shoshany, Tian RuoJin, Miguel Padilla‐Blanco, Adam Hruška, Aditi Konar, Katarína L. Baxová, Eyal Zoler, Martin Mokrejš, Gideon Schreiber, Jiří Zahradník
This study uses in vitro evolution to show that stringent selection pressures rapidly converge on Omicron-like mutations in SARS-CoV-2 spike protein, mirroring real-world viral evolution patterns.
Nature Communications · Apr 25, 2026Peer-reviewedEvolutionary Biology