Author

Jiří Zahradník

Charles UniversityORCID 0000-0002-8698-4236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Eyal ZoleriD· 2 shared Gideon SchreiberiD· 2 shared Adam Hruška· 1 shared Aditi Konar· 1 shared Andrea GálisováiD· 1 shared Ariel AfekiD· 1 shared Aviv Shoshany· 1 shared Daniel Harari· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersEvolutionary Biology

Eyal ZolerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In Vitro and Viral Evolution Convergence Reveal the Selective Pressures Driving Omicron Emergence

Aviv Shoshany, Tian RuoJin, Miguel Padilla‐Blanco, Adam Hruška, Aditi Konar, Katarína L. Baxová, Eyal Zoler, Martin Mokrejš, Gideon Schreiber, Jiří Zahradník

This study uses in vitro evolution to show that stringent selection pressures rapidly converge on Omicron-like mutations in SARS-CoV-2 spike protein, mirroring real-world viral evolution patterns.

Nature Communications · Apr 25, 2026Peer-reviewedEvolutionary Biology

Universal functionalization of extracellular vesicles with nanobody adapters

Andrea Gálisová, Jiří Zahradník, Ester Merunkova, Dominik Havlíček, Josef Uskoba, Ziv Porat, Daniel Jirák

This paper introduces a system for functionalizing extracellular vesicles with nanobody adapters, enabling flexible and efficient attachment of target proteins without genetic engineering of cells.

bioRxiv · Mar 3, 2026 · PreprintBioengineering

IRF1 Tunes Basal Immunity and Antiviral Readiness in a Context-Dependent Manner

Eyal Zoler, Irina Miodownik, Shifra Ben‐Dor, Daniel Harari, Jiří Zahradník, Ariel Afek, Gideon Schreiber

This study shows IRF1 regulates antiviral immunity through both cytokine signaling and direct promoter binding, affecting gene expression in a context-dependent manner.

Journal of Biological Chemistry · Dec 30, 2025Peer-reviewedBiochemistry