An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis
Gareth J. Morgan, Allison N. Nau, Sherry Wong, Brian Spencer, Yun Shen, Axin Hua, Matthew J. Bullard, Vaishali Sanchorawala, Tatiana B. Prokaeva
The paper updates the AL-Base database and identifies enriched immunoglobulin light chain variable genes in AL amyloidosis, showing some genes are highly enriched and others have mutation patterns distinct from other conditions.
Amyloid · Dec 6, 2024Peer-reviewedBioinformatics