Transmembrane PhoxID: Photo-proximity labelling across the plasma membrane
Fátima Yuri Tanimura Valor, Mikiko Takato, Ayane Araki, Seiji Sakamoto, Tomonori Tamura, Itaru Hamachi
This paper introduces tmPhoxID, a method to label the cytoplasmic side of transmembrane proteins using singlet oxygen, and demonstrates its application in identifying intracellular interactomes of specific receptors in the mouse brain.
bioRxiv · Jan 15, 2026 · PreprintNeuroscience