Molecular BiologyMolecular TherapyPeer-reviewed
Aberrant Clonal Hematopoiesis Following Lentiviral Transduction of HSPC in a Rhesus Macaque
Diego A. Espinoza, Xing Fan, Di Yang…·Cynthia E. Dunbar
This paper reports a case of clonal hematopoiesis in a rhesus macaque following lentiviral transduction of HSPC with a strong retroviral promoter, leading to gene overexpression and aberrant splicing.
43 citations