Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD
M. Mehedi, J. K. Osan, S. N. Talukdar, F. Feldmann, B. A. DeMontigny, K. Jerome, K. L. Bailey, H. Feldmann
This study shows that goblet cells in COPD patients are more susceptible to SARS-CoV-2 infection due to higher ACE2 and TMPRSS2 expression, leading to increased viral replication.
bioRxiv · Nov 11, 2020 · PreprintMicrobiology