Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.
S. J. Ziegler, C. Liu, M. Landau, O. Buzovetsky, B. A. Desimmie, Q. Zhao, T. Sasaki, R. C. Burdick, V. K. Pathak, K. S. Anderson, Y. Xiong
This study investigates how APOBEC3G selects DNA substrates through structural, biochemical, and functional analyses, revealing key interactions and mechanisms involved in its antiviral activity against HIV-1.
bioRxiv · Dec 16, 2017Biophysics