Cancer BiologybioRxivPreprint
Cell intrinsic signaling in MEN1 mutant pancreatic neuroendocrine tumors unveils novel signaling pathways associated with de-differentiation
B. A. Rheinheimer, R. L. Heimark, A. D. Grant…·T. Jie
The paper identifies MEN1 and FGFR3 mutations in pancreatic neuroendocrine tumors and links them to de-differentiation and aggressiveness, suggesting FGFR3 as a therapeutic target.
DOI 10.1101/2020.09.29.318873