Evolutionary loss of inflammasomes in carnivores to facilitate carriage of zoonotic infections
Z. Digby, J. Rooney, J. P. Boyle, B. B. Verdugo, R. Pickering, S. J. Webster, T. Monie, L. Hopkins, N. Kayagaki, G. Salvesen, S. Warming, L. Weinert, C. E. Bryant
The paper investigates evolutionary changes in inflammasome pathways in carnivores, finding reduced immune sensing that may facilitate zoonotic pathogen carriage.
bioRxiv · Dec 7, 2020 · PreprintImmunology