Polyunsaturated fatty acid analogues differentially affect cardiac Nav, Cav, and Kv channels through unique mechanisms
B. Bohannon, X. Wu, M. Perez, S. I. Liin, H. P. Larsson
This study shows that PUFA analogues differentially modulate cardiac ion channels through distinct mechanisms, suggesting potential tailored therapies for specific LQTS mutations.
bioRxiv · Sep 19, 2019Biophysics