Author

S. I. Liin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Organism:Xenopus· 1

Frequent Co-Authors

H. P. Larsson· 2 shared B. Bohannon· 1 shared B. M. Bohannon· 1 shared D. J. Frampton· 1 shared J. J. Jowais· 1 shared J. Nikesjö· 1 shared L. Nyberg· 1 shared M. Perez· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 13 mutual co-author links

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2 shared papersPhysiology

H. P. Larsson

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3 papers

Recent·Most cited

Mechanistic insights into robust cardiac IKs potassium channel activation by aromatic polyunsaturated fatty acid analogues

B. M. Bohannon, J. J. Jowais, L. Nyberg, S. I. Liin, H. P. Larsson

The paper identifies aromatic PUFA analogues that activate the cardiac IKs channel through hydrogen bonding and ionic interactions, not cation-pi interactions.

bioRxiv · Jan 12, 2023Physiology

Subtype specific responses in hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids

D. J. Frampton, J. Nikesjö, S. I. Liin

This study investigates how polyunsaturated fatty acids (PUFAs) differentially affect KV7.4 and KV7.5 channels, showing activation in KV7.5 and inhibition in KV7.4 with voltage-dependent effects.

bioRxiv · Aug 20, 2021Biophysics

Polyunsaturated fatty acid analogues differentially affect cardiac Nav, Cav, and Kv channels through unique mechanisms

B. Bohannon, X. Wu, M. Perez, S. I. Liin, H. P. Larsson

This study shows that PUFA analogues differentially modulate cardiac ion channels through distinct mechanisms, suggesting potential tailored therapies for specific LQTS mutations.

bioRxiv · Sep 19, 2019Biophysics