Targeting interferon-{lambda} signaling promotes recovery from central nervous system autoimmunity
S. Manivasagam, J. L. Williams, L. L. Vollmer, B. Bollman, J. M. Bartleson, S. Ai, G. F. Wu, R. S. Klein
This study shows that blocking IFNL signaling reduces autoimmune inflammation in MS by impairing T cell effector function and APC activity.
bioRxiv · Aug 17, 2021Immunology