Mitochondrial active Ras2 protein promotes apoptosis and regulated cell death in a cAMP/PKA pathway-dependent manner in budding yeast.
B. Bonomelli, E. Martegani, S. Colombo
The paper shows that mitochondrial active Ras2 promotes apoptosis via the cAMP/PKA pathway in budding yeast, while Ras1 is involved in pro-survival mechanisms.
bioRxiv · Oct 13, 2021 · PreprintMicrobiology