Author

B. C. Christensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Pathology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

D. R. Pattabiraman· 2 shared K. E. Muller· 2 shared L. A. Salas· 2 shared L. J. Vaickus· 2 shared M. K. Lee· 2 shared C. Bobak· 1 shared C. C. Haudenschild· 1 shared C. R. Jackson· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

D. R. Pattabiraman

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Normal gastric tissue Helicobacter pylori infection is associated with epigenetic age acceleration, increased mitotic tick rate, tissue cell composition, and Natural Killer cell methylation alterations

I. M. Vlasac, L. A. Salas, B. C. Christensen

The paper examines DNA methylation changes in normal gastric mucosa from H. pylori-infected individuals with and without gastric cancer, finding epigenetic age acceleration, increased mitotic activity, and immune cell composition differences.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Alteration of DNMT1/DNMT3A by eribulin elicits global DNA methylationchanges with potential therapeutic implications for triple-negative breastcancer

M. Bagheri, M. K. Lee, K. E. Muller, T. W. Miller, D. R. Pattabiraman, B. C. Christensen

This study shows eribulin treatment alters DNA methylation and epigenetic modifier expression in TNBC cells, suggesting potential therapeutic use in triple-negative breast cancer.

bioRxiv · Jun 9, 2023 · PreprintCancer Biology

Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits

G. A. Mohamed, S. Mahmood, N. B. Ognjenovic, M. K. Lee, O. M. Wilkins, B. C. Christensen, K. E. Muller, D. R. Pattabiraman

The paper shows low-ER luminal breast tumors can evolve into basal-like traits through lineage plasticity, with SOX10 identified as a potential driver.

bioRxiv · Nov 25, 2022Cancer Biology

Mixed Effects Machine Learning Models for Colon Cancer Metastasis Prediction using Spatially Localized Immuno-Oncology Markers

J. Levy, C. Bobak, M. Nasir-Moin, E. M. Veziroglu, S. M. Palisoul, R. E. Barney, L. A. Salas, B. C. Christensen, G. J. Tsongalis, L. J. Vaickus

This study uses mixed-effects machine learning to predict colon cancer metastasis by analyzing spatially localized immuno-oncology markers in tumor tissue.

bioRxiv · Aug 1, 2021Pathology

PathFlow-MixMatch for Whole Slide Image Registration: An Investigation of a Segment-Based Scalable Image Registration Method

J. J. Levy, C. R. Jackson, C. C. Haudenschild, B. C. Christensen, L. J. Vaickus

The paper introduces a segment-based image registration method for whole slide images, showing improved alignment accuracy compared to full image registration.

bioRxiv · Mar 22, 2020 · PreprintPathology