Vertical Sleeve Gastrectomy Induces Enteroendocrine Cell Differentiation of Intestinal Stem Cells Through Farnesoid X Receptor Activation
K.-S. Kim, B. C. E. Peck, Y.-H. Hung, K. L. Koch-Laskowski, L. Wood, P. H. Dedhia, J. R. Spence, R. J. Seeley, P. Sethupathy, D. A. Sandoval
This study shows vertical sleeve gastrectomy increases enteroendocrine cells via FXR activation in intestinal stem cells, using RNAseq and organoid experiments.
bioRxiv · Apr 22, 2021 · PreprintPhysiology