L. Wood

Characterisation of the butyrate production pathway in probiotic MIYAIRI588 by a combined whole genome-proteome approach.

This study identifies rate-limiting enzymes in the butyrate production pathway of probiotic MIYAIRI588 using genome and proteome analysis.

Mechanical loading of the Achilles tendon during different rehabilitation exercises: A cross sectional observational study.

This study compares force fluctuations in the Achilles tendon during two rehabilitation exercises, finding that eccentric heel drops produce significantly greater force variation than a walking drill.

Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle

This study investigates how increased tendon compliance affects muscle spindle firing during different stretch types and finds that firing rates are generally reduced but not fully explained by fascicle length and velocity.

Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

This study identifies a mechanotransductive feedback loop involving YAP and TAZ that regulates endothelial cell motility and vascular morphogenesis in vitro and in vivo.

Vertical Sleeve Gastrectomy Induces Enteroendocrine Cell Differentiation of Intestinal Stem Cells Through Farnesoid X Receptor Activation

This study shows vertical sleeve gastrectomy increases enteroendocrine cells via FXR activation in intestinal stem cells, using RNAseq and organoid experiments.

Chromosomally unstable tumor cells specifically require KIF18A for proliferation

This study shows KIF18A is essential for proliferation of chromosomally unstable tumor cells but not near-diploid cells, with effects linked to centrosome fragmentation and mitotic defects.

A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions

The paper identifies novel host-pathogen interactions between Plasmodium falciparum sporozoite proteins and human hepatocyte surface receptors using a high-throughput screening assay.

Evolutionary Origins of Recurrent Pancreatic Cancer

This study identifies genetic features of recurrent pancreatic cancer through sequencing and finds that treatment-induced genetic changes and potential second primary tumors influence recurrence.