Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes
A. Janaszkiewicz, A. Toth, Q. Faucher, M. Martin, B. Chantemargue, C. Barin-Le Guellec, P. Marquet, F. Di Meo
This study presents the first robust model of hOAT1 in outward-facing conformation using protein-threading and MD simulations, revealing structural and functional insights into its transport mechanism.
Scientific Reports · Apr 29, 2022Peer-reviewedPharmacology & Toxicology