Author

F. Di Meo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 3 Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:structural biology· 3 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Janaszkiewicz· 4 shared A. Toth· 4 shared P. Marquet· 3 shared Q. Faucher· 3 shared B. Chantemargue· 2 shared C. Barin-Le Guellec· 2 shared H. Arnion· 2 shared V. Crespi· 2 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersPharmacology & Toxicology

A. Janaszkiewicz

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Computational and structural insights into the pre- and post-hydrolysis states of bovine multidrug resistance associated protein 1 (MRP1)

A. Toth, V. Crespi, A. Janaszkiewicz, F. Di Meo

This study uses molecular dynamics simulations to analyze structural changes in bMRP1 before and after hydrolysis, revealing conformational shifts and lipid interactions.

bioRxiv · Dec 27, 2022Pharmacology & Toxicology

Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale

A. Janaszkiewicz, A. Toth, Q. Faucher, H. Arnion, N. Vedrenne, C. Barin-Le Guellec, P. Marquet, F. Di Meo

This study investigates the structure and function of hOAT1 using molecular dynamics simulations, identifying substrate binding sites and allosteric mechanisms involving lipid interactions.

bioRxiv · Jul 14, 2022Pharmacology & Toxicology

On the interplay between lipids and asymmetric dynamics of an NBS degenerate ABC transporter

A. Toth, A. Janaszkiewicz, V. Crespi, F. Di Meo

This study investigates the role of lipids and asymmetric dynamics in the NBS degenerate ABC transporter MRP1 using molecular dynamics simulations, finding limited lipid impact on transport kinetics.

bioRxiv · May 16, 2022Biophysics

Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes

A. Janaszkiewicz, A. Toth, Q. Faucher, M. Martin, B. Chantemargue, C. Barin-Le Guellec, P. Marquet, F. Di Meo

This study presents the first robust model of hOAT1 in outward-facing conformation using protein-threading and MD simulations, revealing structural and functional insights into its transport mechanism.

Scientific Reports · Apr 29, 2022Peer-reviewedPharmacology & Toxicology

Cyclosporine A inhibits MRTF-SRF signalling through Na+/K+ ATPase inhibition & Actin remodelling

B. Burat, Q. Faucher, P. Cechova, H. Arnion, F. Di Meo, F.-L. Sauvage, P. Marquet, M. Essig

This study identifies a novel pathway by which Cyclosporine A causes nephrotoxicity through Na+/K+-ATPase inhibition and Actin remodelling in renal proximal tubular cells.

bioRxiv · Dec 20, 2018Cell Biology

Nitrone-Trolox conjugate as an inhibitor of lipid oxidation: Towards synergistic antioxidant effects

S. Morandat, P. Trouillas, L. Socrier, G. Durand, M. Rosselin, A. M. Gomez Giraldo, B. Chantemargue, F. Di Meo

The paper designs and tests amphiphilic Trolox-PBN derivatives as lipid oxidation inhibitors, finding synergistic antioxidant effects when both moieties are on the same fluorinated carrier.

bioRxiv · May 16, 2018Biophysics