Identification of Splice Regulators of Fibronectin-EIIIA and EIIIB by Direct Measurement of Exon Usage in a Flow-Cytometry Based CRISPR Screen
J. A. Hensel, B. D. Heineman, A. L. Kimble, E. R. Jellison, B. Reese, P. A. Murphy
The paper develops a flow-cytometry based CRISPR screen to identify splice regulators of fibronectin-EIIIA and EIIIB exons, identifying known and novel regulators and implicating TNFalpha and RIG-I-like signaling pathways.
bioRxiv · May 5, 2021Cell Biology