Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry.
K. Leguay, B. Decelle, I. E. Elkholi, M. Bouvier, J.-F. Cote, S. Carreno
The paper identifies microtubule disassembly as a cell-cycle signal that activates ERMs and drives cell rounding at mitotic entry through a signaling network involving GEF-H1 and Ect2.
bioRxiv · Jun 14, 2021Cell Biology