Author

B. Deflandre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:bacteria (other)· 4 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:plant (other)· 1

Frequent Co-Authors

S. Rigali· 7 shared B. Devreese· 3 shared I. M. Francis· 3 shared R. Loria· 3 shared S. Jourdan· 3 shared S. Planckaert· 3 shared E. Tenconi· 2 shared F. Kerff· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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7 shared papersMicrobiology

S. Rigali

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Common scab disease: structural basis of elicitor recognition in pathogenic Streptomyces species

F. Kerff, S. Jourdan, I. M. Francis, B. Deflandre, S. Ribeiro Monteiro, N. Stulanovic, R. Loria, S. Rigali

This paper solves the structure of CebE from Streptomyces scabiei bound to cellotriose, revealing its role in pathogenicity and conserved signaling pathways in common scab-causing species.

bioRxiv · May 10, 2023Microbiology

Structure and function of BcpE2, the most promiscuous GH3-family beta-glucosidase for scavenging glucose from heterosides

B. Deflandre, C. Jadot, S. Planckaert, N. Thiebaut, N. Stulanovic, R. Herman, B. Devreese, F. Kerff, S. Rigali

This study identifies BcpE2 as a highly promiscuous GH3-family beta-glucosidase in Streptomyces scabiei that hydrolyzes diverse plant-derived heterosides, enabling glucose scavenging and virulence modulation.

bioRxiv · Jan 22, 2022 · PreprintBiochemistry

BglC of Streptomyces scabiei is a scopolin-hydrolyzing β-glucosidase interfering with the host defense mechanism

B. Deflandre, S. Rigali

This study identifies BglC as a β-glucosidase in Streptomyces scabiei that hydrolyzes scopolin, a host defense phytoalexin, and modulates virulence by affecting thaxtomin A production.

bioRxiv · Oct 20, 2021 · PreprintMicrobiology

The virulome of Streptomyces scabiei in response to cello-oligosaccharides elicitors

B. Deflandre, N. Stulanivic, S. Planckaert, S. Anderssen, B. Bonometti, L. Karim, W. Coppieters, B. Devreese, S. Rigali

This paper identifies virulome molecules and biosynthetic gene clusters in Streptomyces scabiei 87-22 induced by cello-oligosaccharides, revealing new metabolites and regulatory mechanisms.

bioRxiv · Aug 10, 2021Microbiology

Bagremycin Antibiotics and Ferroverdin iron-chelators are synthetized by the Same Gene Cluster

L. Martinet, A. Naome, B. Deflandre, M. Maciejewska, D. Tellatin, E. Tenconi, N. Smargiasso, E. De Pauw, G. P. van Wezel, S. Rigali

The paper shows that ferroverdins and bagremycins, two metabolites with different bioactivities, are produced from the same BGC, with their formation depending on iron availability.

bioRxiv · May 8, 2019 · PreprintMicrobiology

Contribution of the β-glucosidase BglC to the Onset of the Pathogenic Lifestyle of Streptomyces scabies

S. Jourdan, I. M. Francis, B. Deflandre, E. Tenconi, J. Riley, S. Planckaert, P. Tocquin, L. Martinet, B. Devreese, R. Loria, S. Rigali

This study investigates the role of β-glucosidase BglC in the pathogenic lifestyle of Streptomyces scabies and finds that its inactivation leads to unexpected thaxtomin production patterns.

bioRxiv · Sep 23, 2017Microbiology

Tracking the Subtle Mutations Thriving Host Sensing by the Plant Pathogen Streptomyces scabies

S. Jourdan, I. M. Francis, B. Deflandre, R. Loria, S. Rigali

This paper explores how Streptomyces scabies distinguishes between cello-oligosaccharides from decomposing plant material and those from living plants to trigger virulence.

bioRxiv · Jan 3, 2017Microbiology