Author

B. Galeota-Sprung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

P. D. Sniegowski· 3 shared A. Colato· 2 shared F. Cordero· 2 shared N. W. Hengartner· 2 shared P. J. Gerrish· 2 shared V. Vejalla· 2 shared B. Guindon· 1 shared B. Ycart· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersEvolutionary Biology

P. D. Sniegowski

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4 papers

Recent·Most cited

Natural selection promotes the evolution of recombination 2: during the process of natural selection

P. J. Gerrish, F. Cordero, B. Galeota-Sprung, A. Colato, V. Vejalla, P. D. Sniegowski, N. W. Hengartner

This paper shows that natural selection on heritable variation always creates conditions favoring recombination, regardless of genetic fitness distribution.

bioRxiv · Jun 7, 2021 · PreprintEvolutionary Biology

Natural selection and the advantage of recombination

P. J. Gerrish, B. Galeota-Sprung, F. Cordero, P. D. Sniegowski, A. Colato, N. W. Hengartner, V. Vejalla, J. Chevalier, B. Ycart

This paper shows that natural selection favors poorly-matched gene combinations and creates negative associations, which recombination breaks up, making recombination universally advantageous.

bioRxiv · Aug 28, 2020 · PreprintEvolutionary Biology

The fitness cost of mismatch repair mutators in Saccharomyces cerevisiae: partitioning the mutational load

B. Galeota-Sprung, B. Guindon, P. Sniegowski

The paper estimates mutational load in mismatch repair-deficient yeast by partitioning it into nonlethal and lethal components using competitive fitness and lineage tracking experiments.

bioRxiv · Mar 16, 2020Evolutionary Biology

Mutational load and the functional fraction of the human genome

B. Galeota-Sprung, P. D. Sniegowski, W. Ewens

This paper examines whether mutational load limits the functional fraction of the human genome and finds that such a limit is not strongly constrained by mutational load.

bioRxiv · Mar 16, 2020Evolutionary Biology