Peptidylarginine Deiminase inhibition abolishesthe production of large extracellular vesicles fromGiardia intestinalis, affecting host-pathogeninteractions by hindering adhesion to host cells.
B. Gavinho, I. Rossi, I. Evans-osses, S. Lange, M. I. Ramirez
This study shows that inhibiting peptidylarginine deiminase (PAD) reduces large extracellular vesicle production in Giardia intestinalis, impairing host-pathogen adhesion.
bioRxiv · Apr 4, 2019Microbiology