Development of a first-in-class unimolecular dual GIP/GLP-2 analogue, GL-0001, for the treatment of bone fragility
B. Gobron, M. Couchot, N. Irwin, E. Legrand, B. Bouvard, G. Mabilleau
This paper introduces GL-0001, a dual GIP/GLP-2 analogue that improves bone ECM material properties and prevents trabecular bone degradation in ovariectomized mice.
bioRxiv · Jul 21, 2022Pharmacology & Toxicology