The microbiota and immune system non-genetically affect offspring phenotypes transgenerationally
J. C. Harris, N. A. Trigg, B. Goshu, Y. Yokoyama, L. Dohnalova, E. K. White, A. Harman, C. A. Thaiss, E. A. Grice, C. C. Conine, T. Kambayashi
The paper shows that microbiota and immune system states can transgenerationally affect offspring phenotypes through epigenetic mechanisms in gametes.
bioRxiv · Apr 6, 2023 · PreprintMicrobiology