Author

J. C. Harris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

E. A. Grice· 2 shared E. K. White· 2 shared A. E. Campbell· 1 shared A. Harman· 1 shared A. Rodriguez· 1 shared A. Uberoi· 1 shared B. B. Rees· 1 shared B. Goshu· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

E. A. Grice

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tissue-specific increases in hypoxia-inducible factor 1 alpha protein are independent of mRNA levels during acute hypoxic exposure of the Gulf killifish, Fundulus grandis

T. E. Murphy, J. C. Harris, B. B. Rees

The study measures HIF1 protein and mRNA levels in Gulf killifish tissues during hypoxia, finding protein increases without corresponding mRNA changes, suggesting post-translational stabilization.

bioRxiv · Aug 7, 2023 · PreprintPhysiology

Wound microbiota-mediated correction of matrix metalloproteinase expression promotes re-epithelialization of diabetic wounds

E. K. White, A. Uberoi, J. T.-C. Pan, J. T. Ort, A. E. Campbell, S. M. Murga-Garrido, J. C. Harris, P. Bhanap, M. Wei, N. Y. Robles, S. E. Gardner, E. A. Grice

This study shows that Alcaligenes faecalis treatment corrects matrix metalloproteinase overexpression in diabetic wounds, promoting re-epithelialization.

bioRxiv · Jun 30, 2023 · PreprintMicrobiology

The microbiota and immune system non-genetically affect offspring phenotypes transgenerationally

J. C. Harris, N. A. Trigg, B. Goshu, Y. Yokoyama, L. Dohnalova, E. K. White, A. Harman, C. A. Thaiss, E. A. Grice, C. C. Conine, T. Kambayashi

The paper shows that microbiota and immune system states can transgenerationally affect offspring phenotypes through epigenetic mechanisms in gametes.

bioRxiv · Apr 6, 2023 · PreprintMicrobiology

Artemisinin-based hybrids produce intracellular proteasome inhibitors that overcome resistance in Plasmodium falciparum

W. Zhan, Y. J. Liu, C. Yang, H. Zhang, J. C. Harris, R. Wang, S. Zhu, J. Sherman, G. Sukenick, A. Rodriguez, H. Deng, C. F. Nathan, L. A. Kirkman, G. Lin

This study designs artezomibs, artemisinin-proteasome inhibitor hybrids, which overcome resistance in Plasmodium falciparum by targeting proteasomes, including those with mutations.

bioRxiv · Jun 21, 2021 · PreprintMicrobiology