N-terminal protein acetylation by NatB modulates the levels of Nmnats, the NAD+ biosynthetic enzymes in Saccharomyces cerevisiae
T. Croft, P. Venkatakrishnan, C. James Theoga Raj, B. Groth, T. Cater, S.-J. Lin
This study shows that N-terminal acetylation by NatB regulates Nmnat protein levels in yeast, affecting NAD+ homeostasis through co-translational degradation.
bioRxiv · Oct 29, 2019Biochemistry