Detecting and quantifying clonal selection in somatic stem cells
V. Korber, N. Ansari-Pour, N. A. Jakobsen, R. Moore, N. Claudino, M. Metzner, F. Horsch, B. Usukhbayar, M. A. Salazar, S. Newman, B. J. Kendrick, A. H. Taylor, R. Afinowi-Luitz, R. Gundle, B. Watkins, , T. Hofer
This study introduces SCIFER, a method to detect and quantify clonal selection in somatic stem cells, revealing accelerated stem cell division in clonal hematopoiesis.
bioRxiv · Dec 15, 2021Cancer Biology