Author

B. Usukhbayar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 3 Cell Biology· 1

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

P. Vyas· 4 shared M. Metzner· 3 shared A. H. Taylor· 2 shared A. J. Carr· 2 shared B. Stoilova· 2 shared B. Watkins· 2 shared D. Beazley· 2 shared K. Wheway· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

P. Vyas

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4 papers

Recent·Most cited

Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging

N. A. Jakobsen, S. Turkalj, A. G. X. Zeng, B. Stoilova, M. Metzner, M. S. Nagree, S. Shah, R. Moore, B. Usukhbayar, M. A. Salazar, G.-A. Gafencu, A. Kennedy, S. Newman, B. J. L. Kendrick, A. H. Taylor, , P. Vyas

This study identifies how DNMT3A and TET2 mutations in hematopoietic stem cells confer a selective advantage by reducing inflammation and aging effects.

bioRxiv · Sep 12, 2023 · PreprintCancer Biology

Dysregulation of chromatin via H3K27 methylation underpins differentiation arrest in Isocitrate dehydrogenase-mutant Acute Myeloid Leukaemia.

D. R. Silveira, P. Chatzikyriakou, P. Casares Alaez, S. Mackie, R. Hulks, O. Yavorska, P. Siejka-Zielinska, A. Smith, M. Metzner, B. Usukhbayar, V. Penard-Lacronique, C.-X. Song, A. K. Gandhi, P. Vyas, T. Milne, , L. Quek

This study shows that IDH2 mutations in AML block differentiation by altering H3K27 methylation, and that Enasidenib can reverse this block by modulating chromatin states.

bioRxiv · Aug 24, 2023 · PreprintCancer Biology

Detecting and quantifying clonal selection in somatic stem cells

V. Korber, N. Ansari-Pour, N. A. Jakobsen, R. Moore, N. Claudino, M. Metzner, F. Horsch, B. Usukhbayar, M. A. Salazar, S. Newman, B. J. Kendrick, A. H. Taylor, R. Afinowi-Luitz, R. Gundle, B. Watkins, , T. Hofer

This study introduces SCIFER, a method to detect and quantify clonal selection in somatic stem cells, revealing accelerated stem cell division in clonal hematopoiesis.

bioRxiv · Dec 15, 2021Cancer Biology

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

G. Juban, N. Sakakini, H. Chagraoui, Q. Cheng, K. Soady, B. Stoilova, C. Garnett, D. Waithe, J. Doondeea, B. Usukhbayar, E. Karkoulia, M. Alexiou, J. Strouboulis, E. Morrissey, I. Roberts, , P. Vyas

This study identifies stage-specific differentiation delays caused by GATA1s in megakaryocytes, leading to increased immature cells and altered gene expression.

bioRxiv · Oct 3, 2019Cell Biology