Molecular basis for GIGYF-TNRC6 complex assembly in miRNA-mediated translational repression
M. Sobti, B. J. Mead, C. Igreja, A. G. Stewart, M. Christie
This study determines the crystal structures of GIGYF1/2 GYF domains interacting with TNRC6 proteins, revealing how they bridge 4EHP to miRNA targets for translational repression.
bioRxiv · Aug 20, 2021 · PreprintBiochemistry