Three-Compartment Model of CAR T-cell Immunotherapy
B. J. Rodrigues, L. R. C. Barros, R. C. Almeida
This paper develops a three-compartment mathematical model to simulate CAR T-cell immunotherapy outcomes in mice, showing it can represent tumor elimination, equilibrium, and escape based on varying parameters and dosing.
bioRxiv · Apr 18, 2020 · PreprintImmunology