BKV clearance time correlates with exhaustion state and T-cell receptor repertoire shape of BKV-specific T-cells in renal transplant patients
U. Stervbo, M. Nienen, B. J. Weist, L. Kuchenbecker, P. Wehler, T. H. Westhoff, P. Reinke, N. Babel
The paper investigates factors affecting BKV clearance in kidney transplant patients, finding that T-cell receptor diversity and exhaustion status, not clone numbers, correlate with clearance duration.
bioRxiv · Feb 21, 2019Immunology