Antigen properties shape organization of FcεRI aggregates to tune mast cell signaling
D. A. Rinaldi, W. K. Kanagy, R. M. Grattan, J. C. David, H. C. Kaye, E. A. Burns, S. R. Lucero, M. P. Perez, M. J. Wester, L. Tapia, B. Jacobson, K. A. Lidke, B. S. Wilson, D. S. Lidke
This study shows that antigen properties like valency and epitope spacing shape FcεRI aggregate structure, influencing mast cell signaling outcomes.
bioRxiv · Aug 4, 2023 · PreprintBiophysics