Author

B. Jakob

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. Fournier· 2 shared A. Helm· 1 shared A. Moroni· 1 shared B. Roth· 1 shared C. Totis· 1 shared D. F. Hintze· 1 shared D. H. Tandl· 1 shared F. Roedel· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

C. Fournier

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Induction of cytoplasmic dsDNA and cGAS-STING immune signaling after exposure of breast cancer cells to X-rays or high energetic carbon ions

C. Totis, N. B. Averbeck, B. Jakob, M. Schork, G. Volpi, D. F. Hintze, M. Durante, C. Fournier, A. Helm

This study shows carbon ions induce more cytosolic dsDNA and interferon-β in breast cancer cells than X-rays, enhancing innate immune signaling.

bioRxiv · Jul 23, 2024Biophysics

X-ray Irradiation activates immune response in human T-lymphocytes by eliciting a Ca2+ signaling cascade

G. Thiel, D. H. Tandl, T. Sponagel, S. Fuck, T. Smit, S. Hehlgans, B. Jakob, C. Fournier, F. Roedel, B. Roth, A. Moroni

The paper shows X-ray irradiation triggers a Ca2+ signaling cascade in T-lymphocytes, leading to immune activation through NFAT nuclear translocation.

bioRxiv · Nov 13, 2020Biophysics