KDS2010, a newly developed reversible MAO-B inhibitor, as an effective therapeutic candidate for Parkinson's disease
M.-H. Nam, J.-H. Park, H. J. Song, J. W. Choi, S. Kim, B. K. Jang, H. H. Yoon, J. Y. Heo, D.-W. Cho, Y.-S. Yang, S.-C. Han, S. Kim, S.-J. Oh, S. R. Jeon, K. D. Park, C. J. Lee
This paper tests KDS2010, a reversible MAO-B inhibitor, in PD animal models and finds it effective with low toxicity and superior neuroprotection compared to selegiline.
bioRxiv · Jul 6, 2020Pharmacology & Toxicology