Testing in vitro toxicity of nanoparticles in 3D cell culture with various extracellular matrix scaffold
J. W. Choi, S.-H. Bae, I. Y. Kim, M. Kwak, T. G. Lee, M. B. Heo
This study compares the toxicity of 20 nm SiO2 nanoparticles in 2D and 3D cell cultures using different scaffolds, finding reduced toxicity in 3D cultures and scaffold-dependent effects in serum-free conditions.
bioRxiv · Mar 18, 2021 · PreprintPharmacology & Toxicology