Author

B. Kandasamy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:human· 1

Frequent Co-Authors

C. Yoshioka· 2 shared G. M. Martin· 2 shared S.-L. Shyng· 2 shared F. DiMaio· 1 shared L. David· 1 shared L. M. Innes· 1 shared M. W. Sung· 1 shared Z. Yang· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

C. Yoshioka

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2 papers

Recent·Most cited

Mechanism of pharmacochaperoning in KATP channels revealed by cryo-EM

G. M. Martin, M. W. Sung, Z. Yang, L. M. Innes, B. Kandasamy, L. David, C. Yoshioka, S.-L. Shyng

This study reveals how pharmacochaperones stabilize KATP channels by binding to SUR1 and supporting Kir6.2 N-terminus insertion, enabling mutant channel assembly.

bioRxiv · Mar 8, 2019 · PreprintBiophysics

Anti-diabetic drug binding site in KATP channels revealed by Cryo-EM

G. M. Martin, B. Kandasamy, F. DiMaio, C. Yoshioka, S.-L. Shyng

The paper presents a cryo-EM structure of KATP channels bound to glibenclamide and ATP, revealing the drug's binding site and its interaction with the channel.

bioRxiv · Aug 5, 2017Biochemistry