Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen
F. Khan, T. R. Muller, B. Kasmapour, M. A. Y. Durand, B. Eiz-Vesper, J. v. Einem, D. H. Busch, L. Cicin-Sain
This study develops ARMATA, a method to measure antiviral T-cell activity against HCMV, revealing pp65 antigen recognition occurs before the late virus cycle phase.
bioRxiv · Jul 11, 2023 · PreprintImmunology