Electronic cigarettes induce mitochondrial DNA damage and trigger toll-like receptor 9-mediated atherosclerosis
J. Li, D. L. Huynh, M.-S. Tang, H. Simborio, J. Huang, B. Kosmider, M. B. Steinberg, L. T. T. Le, K. Pham, C. Liu, H. Wang
This study shows that e-cigarette vapor causes mitochondrial DNA damage, which activates TLR9 and promotes atherosclerosis in mice.
bioRxiv · Aug 15, 2020Pharmacology & Toxicology