Orthotopic injection of an established syngeneic mouse oral cancer cell line (MOC1) induces a robust draining lymph node response
V. Kansal, B. L. C. Kinney, N. C. Schmitt
This study shows that injecting MOC1 cells orthotopically in the buccal mucosa of mice leads to tumor growth, lymph node enlargement, and changes in immune cell composition over time.
bioRxiv · Jan 12, 2024 · PreprintCancer Biology