Author

N. C. Schmitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

V. Kansal· 2 shared A. H. K. Ashkezari· 1 shared A. M. Rosado· 1 shared B. Kinney· 1 shared B. L. C. Kinney· 1 shared C. Ge· 1 shared C. Zhu· 1 shared D. M. Francis· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

V. Kansal

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2 papers

Recent·Most cited

Orthotopic injection of an established syngeneic mouse oral cancer cell line (MOC1) induces a robust draining lymph node response

V. Kansal, B. L. C. Kinney, N. C. Schmitt

This study shows that injecting MOC1 cells orthotopically in the buccal mucosa of mice leads to tumor growth, lymph node enlargement, and changes in immune cell composition over time.

bioRxiv · Jan 12, 2024 · PreprintCancer Biology

Tumor microenvironments impair T cell receptor affinity and function

Z. Yuan, M. J. O'Melia, K. Li, J. Lyu, A. M. Rosado, V. E. Watson, A. H. K. Ashkezari, F. Zhou, V. Kansal, B. Kinney, S. Travaglino, L. O. Doudy, R. K. Noel, S. N. Lucas, S. L. Kong, , C. Zhu

This study shows that CD8+ T cells in the tumor microenvironment have reduced TCR-pMHC affinity and function, impairing their anti-tumor activity.

bioRxiv · Sep 11, 2022 · PreprintImmunology