Precision-Cut Liver Slices as an ex vivo model to evaluate antifibrotic therapies for liver fibrosis and cirrhosis
Y. Wang, B. Leaker, G. Qiao, M. Sojoodi, I. R. Eissa, E. T. Epstein, J. Eddy, O. Dimowo, G. M. Lauer, R. T. Chung, M. Qadan, M. Lanuti, B. C. Fuchs, K. K. Tanabe
This study evaluates the use of precision-cut liver slices (PCLS) to detect and quantify antifibrotic responses to erlotinib in murine and human cirrhosis models.
bioRxiv · Oct 30, 2023 · PreprintCell Biology