Author

G. M. Lauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

R. T. Chung· 3 shared N. Alatrakchi· 2 shared N. Hacohen· 2 shared S. Subudhi· 2 shared A. Boonstra· 1 shared A. Cui· 1 shared A. Gehring· 1 shared A. K. Bentzen· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

R. T. Chung

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Author profile →

4 papers

Recent·Most cited

Simultaneous analysis of pMHC binding and reactivity unveils virus-specific CD8 T cell immunity to a concise epitope set

N. P. Kristensen, E. Dionisio, A. K. Bentzen, T. Tamhane, J. S. Kemming, G. Nos, L. F. Voss, U. K. Hansen, G. M. Lauer, S. R. Hadrup

The paper identifies a concise set of 137 virus-specific CD8 T cell epitopes recognized by human T cells, with 84% showing prevalent reactivity and associations with effector and memory phenotypes.

bioRxiv · Nov 6, 2023Immunology

Precision-Cut Liver Slices as an ex vivo model to evaluate antifibrotic therapies for liver fibrosis and cirrhosis

Y. Wang, B. Leaker, G. Qiao, M. Sojoodi, I. R. Eissa, E. T. Epstein, J. Eddy, O. Dimowo, G. M. Lauer, R. T. Chung, M. Qadan, M. Lanuti, B. C. Fuchs, K. K. Tanabe

This study evaluates the use of precision-cut liver slices (PCLS) to detect and quantify antifibrotic responses to erlotinib in murine and human cirrhosis models.

bioRxiv · Oct 30, 2023 · PreprintCell Biology

Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity

A. S. Genshaft, S. Subudhi, A. Keo, J. D. Sanchez Vasquez, N. Conceicao-Neto, D. Mahamed, L. L. Boeijen, N. Alatrakchi, C. Oetheimer, M. Vilme, R. Drake, I. Fleming, N. Tran, C. Tzouanas, J. Joseph-Chazan, , A. Gehring

The paper develops a workflow for collecting and analyzing liver immune cells via fine-needle aspirates and single-cell RNA sequencing to better understand tissue-specific immunity in chronic hepatitis B.

bioRxiv · Nov 30, 2021 · PreprintImmunology

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

P. Tonnerre, D. Wolski, S. Subudhi, J. Al-Jabban, R. C. Hoogeveen, M. Damasio, H. K. Drescher, L. M. Bartsch, D. C. Tully, D. R. Sen, D. J. Bean, J. Brown, A. Torres-Cornejo, M. Robidoux, D. Kvistad, , G. M. Lauer

The paper shows that exhausted CD8 T cells do not fully recover functional memory after antigen removal in chronic HCV infection.

bioRxiv · Apr 3, 2021Immunology