Label-free observation of individual solution phase molecules
L.-M. Needham, C. Saavedra, J. K. Rasch, D. Sole-Barber, B. S. Schweitzer, A. J. Fairhall, C. H. Vollbrecht, B. Mehlenbacher, Z. Zhang, L. Tenbrake, H. Pfeifer, E. R. Chapman, R. H. Goldsmith
This paper introduces a label-free technique to detect individual solution-phase molecules using microcavities, achieving high signal-to-noise ratios and resolving molecular radius and isomer mixtures.
bioRxiv · Mar 24, 2023Biophysics