Increased circulating CD39+FoxP3+CD4+ regulatory T cells in Early Rheumatoid Arthritis facilitate the antiinflammatory action of methotrexate and associate with the clinical response
A. Villalba, L. Nuno, M. Benito-Miguel, B. Nieto-Carvalhal, M. Novella-Navarro, I. Monjo, D. Peiteado, S. Garcia-Carazo, A. Balsa, M.-E. Miranda-Carus
The paper examines the relationship between CD39+FoxP3+CD4+ regulatory T cells and methotrexate response in early rheumatoid arthritis, finding higher Treg39+ frequencies predict better clinical outcomes.
bioRxiv · Oct 10, 2023 · PreprintImmunology