Author

L. Nuno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Villalba· 2 shared A. Balsa· 1 shared A. Puig-Kröger· 1 shared A. Triguero-Martinez· 1 shared B. Nieto-Carvalhal· 1 shared C. Barrio Alonso· 1 shared D. Peiteado· 1 shared G. Jansen· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

A. Villalba

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2 papers

Recent·Most cited

Increased circulating CD39+FoxP3+CD4+ regulatory T cells in Early Rheumatoid Arthritis facilitate the antiinflammatory action of methotrexate and associate with the clinical response

A. Villalba, L. Nuno, M. Benito-Miguel, B. Nieto-Carvalhal, M. Novella-Navarro, I. Monjo, D. Peiteado, S. Garcia-Carazo, A. Balsa, M.-E. Miranda-Carus

The paper examines the relationship between CD39+FoxP3+CD4+ regulatory T cells and methotrexate response in early rheumatoid arthritis, finding higher Treg39+ frequencies predict better clinical outcomes.

bioRxiv · Oct 10, 2023 · PreprintImmunology

The macrophage reprogramming ability of antifolates reveals soluble CD14 as a potential biomarker for methotrexate response in rheumatoid arthritis

S. Fuentelsaz-Romero, C. Barrio Alonso, R. Garcia Campos, M. Torres Torresano, I. Muller, A. Triguero-Martinez, L. Nuno, A. Villalba, R. Garcia-Vicuna, G. Jansen, M. E. Miranda-Carus, I. Gonzalez-Alvaro, A. Puig-Kröger

This study shows that antifolates reprogram macrophages via one-carbon metabolism, revealing soluble CD14 as a biomarker for methotrexate response in rheumatoid arthritis.

bioRxiv · May 11, 2021Immunology