A genome-wide CRISPR interference screen using an engineered trafficking biosensor reveals a role for RME-8 in opioid receptor regulation
B. Novy, H. Adoff, M. De Maria, M. Kampmann, N. Tsvetanova, M. Von Zastrow, B. Lobingier
The paper uses a CRISPR interference screen with a trafficking biosensor to identify genes regulating opioid receptor trafficking, finding RME-8 as a novel regulator.
bioRxiv · Oct 11, 2022Cell Biology