Author

H. Adoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Thomas· 1 shared B. Lobingier· 1 shared B. Novy· 1 shared C. Schultz· 1 shared D. Bejan· 1 shared K. Upadhyaya· 1 shared M. De Maria· 1 shared M. Kampmann· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Thomas

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2 papers

Recent·Most cited

A genetically encoded sensor for real-time monitoring of poly-ADP-ribosylation dynamics in-vitro and in cells

A. Thomas, K. Upadhyaya, D. Bejan, H. Adoff, M. S. Cohen, C. Schultz

This paper introduces a genetically encoded FRET probe (pARS) for real-time monitoring of PARylation dynamics in vitro and in live cells, showing its utility in detecting PARP1 activity and inhibitor potency.

bioRxiv · Jun 11, 2024Biochemistry

A genome-wide CRISPR interference screen using an engineered trafficking biosensor reveals a role for RME-8 in opioid receptor regulation

B. Novy, H. Adoff, M. De Maria, M. Kampmann, N. Tsvetanova, M. Von Zastrow, B. Lobingier

The paper uses a CRISPR interference screen with a trafficking biosensor to identify genes regulating opioid receptor trafficking, finding RME-8 as a novel regulator.

bioRxiv · Oct 11, 2022Cell Biology